CLEC7A Mouse Monoclonal Antibody [Clone ID: BD6]

SKU
TA420139
CLEC7A mouse monoclonal antibody, clone BD6, ALEXA FLUOR® 488,ALEXA FLUOR® 647,FITC,Purified,RPE
  $645.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Clone Name BD6
Application FC
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen NIH3T3 cells expressing full length Beta-glucan receptor.
Specificity DECTIN-1
Buffer Phosphate buffered saline containing 0.09% Sodium Azide (NaN3)
Label: ALEXA FLUOR® 488,ALEXA FLUOR® 647,FITC,Purified,RPE
State: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant Purified IgG - liquid
Concentration lot specific
Conjugation Unconjugated
Storage +4°C, -20°C if preferred
Stability Shelf life: one year from despatch.
Shipping Ambient
Gene Name C-type lectin domain family 7 member A
Database Link
Background Mouse anti Human Dectin-1 antibody, clone BD6 recognizes human Dectin-1, also known as beta-glucan receptor (βGR) or CD369. Dectin-1 is a C-type lectin domain family member. It is a major pathogen pattern-recognition receptor that binds beta-glucans, glucose polymers that form cell-wall components or exopolymers of yeasts, fungi and some bacteria. Beta-glucans have also been used experimentally and therapeutically as immunomodulators that enhance resistance to bacterial, yeast, viral and protozoan infections, as well as tumor formation. Dectin-1 also acts as a co-stimulatory molecule on T-cells to induce their proliferation and is necessary for the TLR2-mediated inflammatory response. It is highly expressed on peripheral blood leukocytes and dendritic cells.Human Dectin-1 has two major (βGR-A and βGR-B) and several minor isoforms. βGR-A and βGR-B differs by the presence and absence, respectively, of a stalk region. Mouse anti Human Dectin-1 antibody, clone BD6 recognizes βGR-A only.
Synonyms BETA GLUCAN RECEPTOR,CD369
Reference Data
Protein Categories CD Markers, Cytokines, Immune system diseases, Intracellular Proteins, Membrane Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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