STMN1 Mouse Monoclonal Antibody [Clone ID: STMN1/8438]
$665.00
5 Days*
Specifications
| Product Data | |
| Clone Name | STMN1/8438 |
|---|---|
| Application | IHC |
| Recommended Dilution | IHC: 1-2 ug/mL |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2b, kappa |
| Clonality | Monoclonal |
| Immunogen | Recombinant fragment of human STMN1 protein (exact sequence is proprietary) |
| Specificity | Ubiquitous. Expression is strongest in fetal and adult brain, spinal cord, and cerebellum, followed by thymus, bone marrow, testis, and fetal liver. Expression is intermediate in colon, ovary, placenta, uterus, and trachea, and is readily detected at substantially lower levels in all other tissues examined. Lowest expression is found in adult liver. Present in much greater abundance in cells from patients with acute leukemia of different subtypes than in normal peripheral blood lymphocytes, non-leukemic proliferating lymphoid cells, bone marrow cells, or cells from patients with chronic lymphoid or myeloid leukemia. Cellular Localization: Cytoplasm. Cytoskeleton. |
| Buffer | 10mM PBS with 0.05% BSA & 0.05% azide |
| Concentration | 200 ug/mL |
| Purification | Protein A/G |
| Conjugation | Unconjugated |
| Storage | Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap. |
| Stability | 24 months from date of receipt |
| Shipping | Blue Ice |
| Predicted Protein Size | 19 kDa |
| Gene Name | stathmin 1 |
| Database Link | |
| Background | Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes. |
| Synonyms | C1orf215; Lag; LAP18; Leukemia associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; Phosphoprotein 19; Phosphoprotein p19; pp17; pp19; Pr22 protein; Prosolin; Protein Pr22; SMN; Stathmin1; STMN 1 |
| Reference Data | |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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