OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Perforin (PRF1) Polyclonal Antibody [Clone ID: dG9]

Be the first to review this product
SKU
TA392972
Anti-Perforin APC
Size:
100 Tests
Conjugation:
Unconjugated
  $450.00
2 Weeks*
Bulk/Customize

Frequently Bought Together (1)

TA811000S beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control 30 ul
$200.00

View other "PRF1" antibodies

Specifications
Specifications
Product Data
Clone Name dG9
Application FC
Recommended Dilution Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.
Reactivity Cow (Does not react with: Mouse), Human
Isotype IgG2b, kappa
Clonality Polyclonal
Immunogen purified granules from human YT lymphoma cell line
Specificity The mouse monoclonal antibody dG9 (also known as deltaG9) recognizes perforin, a 70 kDa protein expressed in cytoplasmic granules of cytotoxic T cells and NK cells.
Buffer Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Format: APC
Label: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Concentration lot specific
Purification *Vargas-Inchaustegui DA, Demberg T, Robert-Guroff M: A CD8α(-) subpopulation of macaque circulatory natural killer cells can mediate both antibody-dependent and antibody-independent cytotoxic activities. Immunology. 2011 Nov;134(3):326-40., URL: http://www.ncbi.nlm.nih.gov/pubmed/21978002,*Takeuchi M, Inoue T, Otani T, Yamasaki F, Nakamura S, Kibata M: Cell-in-cell structures formed between human cancer cell lines and the cytotoxic regulatory T-cell line HOZOT. J Mol Cell Biol. 2010 Jun;2(3):139-51., URL: http://www.ncbi.nlm.nih.gov/pubmed/20348186 ,*Qiu Y, Chen J, Liao H, Zhang Y, Wang H, Li S, Luo Y, Fang D, Li G, Zhou B, Shen L, Chen CY, Huang D, Cai J, Cao K, Jiang L, Zeng G, Chen ZW: Tim-3-expressing CD4+ and CD8+ T cells in human tuberculosis (TB) exhibit polarized effector memory phenotypes and stronger anti-TB effector functions. PLoS Pathog. 2012;8(11):e1002984., URL: http://www.ncbi.nlm.nih.gov/pubmed/23144609 ,*Hersperger AR, Makedonas G, Betts MR: Flow cytometric detection of perforin upregulation in human CD8 T cells. Cytometry A. 2008 Nov;73(11):1050-7., URL: http://www.ncbi.nlm.nih.gov/pubmed/18615597 ,*Hameed A, Olsen KJ, Cheng L, Fox WM, Hruban RH, Podack ER: Immunohistochemical identification of cytotoxic lymphocytes using human perforin monoclonal antibody. Am J Pathol. 1992 May;140(5):1025-30., URL: https://www.ncbi.nlm.nih.gov/pubmed/1374586
Conjugation Unconjugated
Storage Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Gene Name perforin 1
Database Link
Synonyms PRF1, P1, PFP, HPLH2
Reference Data
Protein Categories ADC Targets, Cancer: Haematopoietic and Lymphoid, Cardiovascular diseases, Immune system diseases, Intracellular Proteins
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products