Stat5 (phospho-S726/731) Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB:1/500-1000;IHC:1/50-200 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide derived from human stat5a around the phosphorylation site of S726. |
| Specificity | Stat5 (phospho-S726/731) polyclonal antibody detects endogenous levels of Stat5a protein only when phosphorylated at Ser726 and/or Stat5b protein only when phosphorylated at Ser731. |
| Buffer | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
| Concentration | 1mg/ml |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | ~ 90 kDa |
| Database Link | |
| Background | Stat 5a protein is a transcription factor activated by hormone and cytokines. Two highly related, but distinct Stat 5 genes (Stat 5a and Stat 5b) were identified in mouse. The amino acid sequences of Stat 5a and Stat 5b show 96% sequence similarity, and both proteins are co expressed in most tissues of both virgin and lactating mice. However, differential accumulation of Stat 5a and Stat 5b mRNA has been reported for both muscle and mammary tissue. Stat 5a is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth. |
| Synonyms | Signal transducer and activator of transcription 5A; Signal transducer and activator of transcription 5B; STAT5; STAT5A; STAT5B |
| Note | For research use only, not for use in diagnostic procedure. |
| Reference Data | |
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