Phospho Calnexin (Ser583) Rabbit Polyclonal Antibody

SKU
TA392912
Calnexin (phospho-S583) polyclonal antibody
  $340.00
7 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IHC, IP, WB
Recommended Dilution WB:1/10000-50000;IHC:1/50-1000;IP:1/50-200
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic phosphopeptide derived from human Calnexin around the phosphorylation site of Serine 583.
Specificity p-Calnexin (S583) polyclonal antibody detects endogenous levels of Calnexin protein only when phosphorylated at Ser583
Buffer Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration 1mg/ml
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Stability 1 year
Shipping Blue Ice
Predicted Protein Size ~ 90 kDa
Gene Name calnexin
Database Link
Background Calnexin and Calregulin (also called Calreticulin) are calcium-binding proteins that are localized to the endoplasmic reticulum—Calnexin to the membrane and Calregulin to the lumen. Calnexin is a type I membrane protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may play a role in assisting with protein assembly and in retaining unassembled protein subunits in the endoplasmic reticulum. Calregulin has both low- and high-affinity calcium-binding sites. Neither Calnexin nor Calregulin contains the calcium-binding “E-F hand” motif found in calmodulins. Calnexin and Calregulin are important for the maturation of glycoproteins in the endoplasmic reticulum and appear to bind many of the same proteins.
Synonyms Calnexin; CANX; IP90; Major histocompatibility complex class I antigen-binding protein p88; p90
Note For research use only, not for use in diagnostic procedure.
Reference Data
Protein Categories Intracellular Proteins, Membrane Proteins
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