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Phospho WNK1 (Thr60) Rabbit Polyclonal Antibody

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SKU
TA392897
WNK1 (phospho-T60) polyclonal antibody
Size:
100 ul
Conjugation:
Unconjugated
  $340.00
7 Weeks*
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Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB:1/500-1000;IHC:1/50-200
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic phosphopeptide derived from human WNK1 around the phosphorylation site of Threonine 60.
Specificity p-WNK1 (T60) polyclonal antibody detects endogenous levels of WNK1 protein only when phosphorylated at Thr60.
Buffer Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration 1mg/ml
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Stability 1 year
Shipping Blue Ice
Predicted Protein Size ~ 251 kDa
Gene Name WNK lysine deficient protein kinase 1
Database Link
Background WNK1 (WNK lysine deficient protein kinase 1), also known as KDP (kinase deficient protein), PSK, erythrocyte 65 kDa protein (p65), HSN2, HSAN2 or PRKWNK1, is a 2,382 amino acid cytoplasmic protein that participates in cell signaling, proliferation and survival, and regulates electrolyte homeostasis. WNK1 belongs to the Ser/Thr protein kinase family of the protein kinase superfamily, and contains one protein kinase domain. Existing as five alternatively spliced isoforms, WNK1 is widely expressed but is found at highest levels in skeletal muscke, heart, testis and kidney. The gene that encodes WNK1 maps to human chromosome 12p13.33, and when defective, is the cause of an an autosomal dominant disease known as pseudohypoaldosteronism type II (PHAII), as well as a hereditary sensory and autonomic neuropathy designated hereditary sensory and autonomic neuropathy type 2A (HSAN2A).
Synonyms Erythrocyte 65 kDa protein; HSN2; hWNK1; KDP; KIAA0344; Kinase deficient protein; PRKWNK1; Protein kinase lysine-deficient 1; Protein kinase with no lysine 1; Serine/threonine-protein kinase WNK1; WNK
Note For research use only, not for use in diagnostic procedure.
Reference Data
Protein Categories Chemokines, Enzyme: Kinases, Intracellular Proteins, Nervous system Diseases
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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