Phospho Smad3 (Ser204) Rabbit Polyclonal Antibody

SKU
TA392657
Smad3 (phospho-S204) polyclonal antibody
  $340.00
7 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB:1:500~1:1000
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic phosphopeptide derived from human Smad3 around the phosphorylation site of Serine 204.
Specificity p-Smad3 (S204) polyclonal antibody detects endogenous levels of Smad3 protein only when phosphorylated at Ser204.
Buffer Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Concentration 1mg/ml
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Stability 1 year
Shipping Blue Ice
Predicted Protein Size ~ 48, 55 kDa
Gene Name SMAD family member 3
Database Link
Background Smad proteins, the mammalian homologs of the Drosophila mothers against decapentaplegic (Mad), have been implicated as downstream effectors of GFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1) and Smad5 are effectors of BMP-2 and BMP-4 function, while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad proteins.
Synonyms hMAD-3; hSMAD3; JV15-2; Mad3; MADH3; MAD homolog 3; Mothers against decapentaplegic homolog 3; Mothers against DPP homolog 3; SMAD 3; SMAD3; Smad3; SMAD family member 3
Note For research use only, not for use in diagnostic procedure.
Reference Data
Protein Categories Growth Factors, Intracellular Proteins, Transciption Factors
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