CD48 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB: 1:1000~1:2000 |
| Reactivity | Human, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human CD48. |
| Specificity | CD48 polyclonal antibody detects endogenous levels of CD48 protein. |
| Buffer | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2. |
| Concentration | 1mg/ml |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | ~ 48 kDa |
| Gene Name | CD48 molecule |
| Database Link | |
| Background | CD48 is a glycosylphosphatidylinositol (GPI) -anchored membrane protein of the signaling lymphocyte activation molecule (SLAM) family, also known as SLAMF2 and BLAST-1. It is constitutively expressed on most hematopoietic cells (not on neutrophils and a subset of long-term hematopoietic stem cells in mice) and can be upregulated under certain conditions like infection. Interaction with its low affinity ligand CD2 promotes adhesion and TCR signaling. Interaction with the high affinity ligand CD244 (2B4) regulates natural killer (NK) and CD8 T cell activation and cytolytic function. |
| Synonyms | B-lymphocyte activation marker BLAST-1; BCM1; BCM1 surface antigen; BLAST1; CD48; CD48 antigen; CD_antigen: CD48; Leukocyte antigen MEM-102; Signaling lymphocytic activation molecule 2; SLAMF2; SLAM family member 2; TCT.1 |
| Note | For research use only, not for use in diagnostic procedure. |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Membrane Proteins, Secreated Proteins |
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