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L1CAM Rabbit Polyclonal Antibody

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SKU
TA392403
CD171/N-CAML1 polyclonal antibody
Size:
100 ul
Conjugation:
Unconjugated
  $340.00
7 Weeks*
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Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB: 1:1000~1:2000
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant protein of human CD171/N-CAML1.
Specificity CD171/N-CAML1 polyclonal antibody detects endogenous levels of CD171/N-CAML1 protein.
Buffer Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Concentration 1mg/ml
Conjugation Unconjugated
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Stability 1 year
Shipping Blue Ice
Predicted Protein Size ~ 200 kDa
Gene Name L1 cell adhesion molecule
Database Link
Background Neural cell adhesion molecule L1 (NCAM-L1/L1CAM) is a single pass transmembrane glycoprotein member of the immunoglobulin superfamily, containing six amino-terminal extracellular Ig-like domains followed by five fibronectin type-III domains. NCAM-L1 is mainly expressed in the brain, and plays an important role in the developing nervous system, with involvement in neurite fasciculation and outgrowth, myelination, neuronal migration, and neuronal cell adhesion. Mutations in the NCAM-L1 gene cause varying degrees of neurological disease including X-linked hydrocephalus, MASA syndrome, spastic paraplegia type 1, and X-linked corpus callosum agenesis, together known as L1 syndrome. Apart from the nervous system, NCAM-L1 is overexpressed in many cancers and supports a poor prognosis by facilitating aggressive tumor growth, metastasis, and chemoresistance.
Synonyms CAML1; CD171; L1CAM; MIC5; N-CAM-L1; NCAM-L1; Neural cell adhesion molecule L1
Note For research use only, not for use in diagnostic procedure.
Reference Data
Protein Categories ADC Targets, CAR-T Targets, CD Markers, Intracellular Proteins, Membrane Proteins, Nervous system Diseases
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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