CD59 Mouse Monoclonal Antibody [Clone ID: 193-27]
Specifications
| Product Data | |
| Clone Name | 193-27 |
|---|---|
| Application | FC, IF, IHC |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgM, kappa |
| Clonality | Monoclonal |
| Immunogen | This antibody was raised by immunizng mice with stimulated human leukocytes. |
| Specificity | This antibody recognizes human CD59 which is a glycosyl phosphatidyl-inositol (GPI)-anchored cell surface protein. It regulates complement-mediated cell lysis, and is involved in lymphocyte signal transduction. The antibody 193-27 is recommended for the identification and analysis of CD59 via various experimental techniques (Bellosillo et al., 2001). Genetic defects in GPI-anchor attachment, that cause a reduction or loss of CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal hemoglobinuria (PNH) and thus this antibody is useful for study on GPI-anchored proteins, PNH and CD59 functions. |
| Buffer | PBS with 0.02% Proclin 300. |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles. |
| Stability | 3 years from dispatch. |
| Shipping | Blue Ice |
| Gene Name | CD59 molecule |
| Database Link | |
| Synonyms | 1F5; 16.3A5; EJ16; EJ30; EL32; FLJ38134; FLJ92039; G344; HRF-20; HRF20; MAC-IP; MACIF; MEM43; MGC2354; MIC11; MIN1; MIN2; MIN3; MIRL; MSK21; p18-20; protectin |
| Reference Data | |
| Protein Categories | CD Markers, Immune system diseases, Intracellular Proteins, Membrane Proteins |
Reviews
Documents
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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