Serotonin transporter (SLC6A4) Mouse Monoclonal Antibody [Clone ID: 8B6]
Specifications
| Product Data | |
| Clone Name | 8B6 |
|---|---|
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG2a, kappa |
| Clonality | Monoclonal |
| Immunogen | 8B6 was produced by immunising SERT KO mice with residues 73-616 of wildtype human SERT. Hybridomas were generated using established protocols. |
| Specificity | The 8B6 Fab binds to extracellular loops 2 and 4 of hSERT, as shown by crystallography (Coleman et al, 2016). The 8B6 Fab fragment was crystallised in complex with human SERT to aid structure determination (Coleman et al, 2016). |
| Buffer | PBS with 0.02% Proclin 300. |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles. |
| Stability | 3 years from dispatch. |
| Shipping | Blue Ice |
| Gene Name | solute carrier family 6 member 4 |
| Database Link | |
| Synonyms | 5-HTT; 5-HTTLPR; 5HTT; hSERT; HTT; OCD1; OTTHUMP00000163633; SERT |
| Reference Data | |
| Protein Categories | Membrane Proteins |
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