Pdcd1lg2 Rabbit Monoclonal Antibody [Clone ID: TY25]
Specifications
| Product Data | |
| Clone Name | TY25 |
|---|---|
| Application | Bl, FC, IP, WB |
| Reactivity | Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG, kappa |
| Clonality | Monoclonal |
| Immunogen | This antibody was raised by immunising SD rats with B7-DC-transfected RAW264.7 cells and selected on B7-DC-transfected NRK. |
| Specificity | This antibody binds to mouse PD-L2 and competes with PD-1 binding. It does not cross-react with PD-L1. This antibody has been used to detect murine PD-L2 by flow cytometry on stimulated dendritic cells as well as various mouse tumour cells. It also detects immunoprecipitates mouse PD-L2 and can be used to detect it by non-reducing Western Blot. TY25 inhibits PD-L2 binding to PD-1 transfected cells (Ansari et al. 2003, PMID: 12847137) and thereby blocks PD-L2 : PD-1 signalling. |
| Buffer | PBS with 0.02% Proclin 300. |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles. |
| Stability | 3 years from dispatch. |
| Shipping | Blue Ice |
| Gene Name | programmed cell death 1 ligand 2 |
| Database Link | |
| Synonyms | B7-DC; B7DC; bA574F11.2; Btdc; CD273; MGC142238; MGC142240; PD-L2; PDCD1L2; PDL2 |
| Note | This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques. |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Membrane Proteins, Secreated Proteins |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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