CD55 Mouse Monoclonal Antibody [Clone ID: LU30]
Specifications
| Product Data | |
| Clone Name | LU30 |
|---|---|
| Application | ELISA, IHC, WB |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1, lambda |
| Clonality | Monoclonal |
| Immunogen | Human CD55. |
| Specificity | The antibody binds to CD55 with a Kd of 13 nM. The antibody binds specifically to CD55, a glycophosphatidylinositol-anchored protein which acts together with CD46 and CD59 to protect cells from complement-mediated cell lysis. The antigen recognises C4b, C3 and C3b complement components, and, by blocking their catalytic activity, inhibits the formation of the membrane attack complex. CD55 is overexpressed in many tumour cell lines, thereby inhibiting complement-mediated cell lysis and increases tumour resistance to immune attacks. |
| Buffer | PBS with 0.02% Proclin 300. |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles. |
| Stability | 3 years from dispatch. |
| Shipping | Blue Ice |
| Gene Name | CD55 molecule (Cromer blood group) |
| Database Link | |
| Synonyms | CR; CROM; DAF; TC |
| Note | This chimeric mouse antibody was made using the variable domain sequences of the original Human format, for improved compatibility with existing reagents, assays and techniques. |
| Reference Data | |
| Protein Categories | CD Markers, Cytokines, Immune system diseases, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
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