CD4 Rabbit Monoclonal Antibody [Clone ID: MT310]
Specifications
| Product Data | |
| Clone Name | MT310 |
|---|---|
| Application | FC, IF, IHC, IP, WB |
| Reactivity | Human, Monkey |
| Antibody Host | Rabbit |
| Isotype | IgG, kappa |
| Clonality | Monoclonal |
| Specificity | mt310 binds to the extracellular domain D1 of CD4 – the same site as the HIV-1 gp120-binding site mt310 can inhibit gp120 binding to CD4, which blocks HIV infectivity of CD4+ T lymphocytes, as well as the binding of MHCII, which results in the block of T-cell activation, possibly leading to the induction of anergy. Antibody binding to CD4 additionally causes the induction of GM-CSF, TNF-α (only after 20 h) and IL-10. |
| Buffer | PBS with 0.02% Proclin 300. |
| Concentration | lot specific |
| Conjugation | Unconjugated |
| Storage | Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles. |
| Stability | 3 years from dispatch. |
| Shipping | Blue Ice |
| Gene Name | CD4 molecule |
| Database Link | |
| Synonyms | CD4mut |
| Note | This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Reference Data | |
| Protein Categories | ADC Targets, CD Markers, Immune system diseases, Intracellular Proteins, Membrane Proteins |
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