Phospho p53 (Ser15) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, ICC, WB |
|---|---|
| Recommended Dilution | WB:1/500-1000 ICC/IF:1/50-200 ELISA:Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| Reactivity | Human, Mouse, Rat |
| Modification | Phospho S15 |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Buffer | Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 44kDa |
| Gene Name | tumor protein p53 |
| Database Link | |
| Background | This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). |
| Synonyms | FLJ92943; LFS1; p53; TRP53 |
| Reference Data | |
| Protein Categories | ADC Targets, Cancer: Bladder, Cancer: Brain and CNS, Cancer: Endocrine, Cancer: Gastrointestinal, Cancer: Gynecologic, Cancer: Haematopoietic and Lymphoid, Cancer: Head and Neck, Cancer: Lung, Cancer: Sarcoma, Cancer: Skin, Cardiovascular diseases, Growth Factors, Intracellular Proteins, Nervous system Diseases, Transciption Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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