HDJ2 (DNAJA1) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, ICC/IF, WB |
|---|---|
| Recommended Dilution | WB,1:1000 - 1:5000 IF/ICC,1:50 - 1:200 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| Reactivity | Human, Mouse, Rat |
| Modification | Unmodified |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Buffer | Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 45kDa |
| Gene Name | DnaJ heat shock protein family (Hsp40) member A1 |
| Database Link | |
| Background | This gene encodes a member of the DnaJ family of proteins, which act as heat shock protein 70 cochaperones. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregation, and proteolytic degradation. Members of this family are characterized by a highly conserved N-terminal J domain, a glycine/phenylalanine-rich region, four CxxCxGxG zinc finger repeats, and a C-terminal substrate-binding domain. The J domain mediates the interaction with heat shock protein 70 to recruit substrates and regulate ATP hydrolysis activity. In humans, this gene has been implicated in positive regulation of virus replication through co-option by the influenza A virus. Several pseudogenes of this gene are found on other chromosomes. |
| Synonyms | DJ-2; DjA1; DNAJ2; hDJ-2; HDJ2; HSDJ; HSJ-2; HSJ2; HSPF4 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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