FACL4 (ACSL4) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, ICC/IF, IHC, IP, WB |
|---|---|
| Recommended Dilution | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| Reactivity | Human, Mouse, Rat |
| Modification | Unmodified |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Buffer | Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 79kDa |
| Gene Name | acyl-CoA synthetase long-chain family member 4 |
| Database Link | |
| Background | The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the cognitive disability or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants. |
| Synonyms | ACS4; FACL4; LACS4; MRX63; MRX68 |
| Reference Data | |
| Protein Categories | Enzyme: Ligase, Intracellular Proteins, Membrane Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
The ovarian tumor domain-containing protein 4 (OTUD4)-targeted ferroptosis inhibitor Maclekarpine E attenuates ulcerative colitis
Lv, He, Xue et al
Phytomedicine (2026) 153, 157999 DOI: 10.1016/j.phymed.2026.157999
Lv, He, Xue et al
Phytomedicine (2026) 153, 157999 DOI: 10.1016/j.phymed.2026.157999
Cited by 1
AI Summary: In this study, the OriGene antibody against ACSL4 (TA373213) was used to assess the expression of ACSL4, a key regulator of ferroptosis, thereby helping to elucidate the molecular mechanism by which Maclekarpine E attenuates ulcerative colitis.
Snippet: CSL4 (1:1000, TA373213, OriGene);HO-1 (1:1000, 10,701-1-AP, Proteintech);p-P65 (1:2000, AP1294, Abclonal);NRF2 (1:2000, 80,593-1-RR, Proteintech)
Showing 1-1 of 1 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
