MRI1 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 200-1000 WB positive control: PC-3 cell,Human bladder transitional cell carcinoma grade 2-3 tissue,231 cell lysates IHC: 30-150 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm and Nucleus |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MRI1 |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | 40 kDa |
| Gene Name | methylthioribose-1-phosphate isomerase 1 |
| Database Link | |
| Background | This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD). |
| Synonyms | M1Pi; MGC3207; MTNA; Ypr118w |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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