ZNF143 Rabbit Polyclonal Antibody

SKU
TA371998
ZNF143 rabbit polyclonal antibody
  $310.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 10-50
Positive control: Human liver cancer
Predicted cell location: Nucleus
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human ZNF143
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C.
Stability 1 year
Shipping Blue Ice
Gene Name zinc finger protein 143
Database Link
Background ZNF143 (zinc finger protein 143), also known as SBF, STAF or pHZ-1, is a 626 amino acid protein that contains seven C2H2-type zinc fingers and belongs to the GLI (glioma-associated oncogene) C2H2-type zinc-finger family. Localized to the nucleus and expressed ubiquitously with highest expression in ovaries, ZNF143 functions as a transcriptional activator that, via its C2H2-type zinc domains, binds to the SPH motif found in the promotors of small nuclear RNAs (snRNA). Through its ability to bind the promotors of various snRNA genes, ZNF143 controls the subsequent expression of the corresponding protein products. ZNF143 expression is induced upon DNA damage, suggesting an important role for ZNF143 in DNA repair events.
Synonyms hStaf; pHZ-1; SBF; STAF
Reference Data
Protein Categories Intracellular Proteins, Transciption Factors
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