C17orf27 (RNF213) Rabbit Polyclonal Antibody

SKU TA371013

RNF213 rabbit polyclonal antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 50-200; Positive control: Human tonsil; Predicted cell location: Cytoplasm
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein of human RNF213
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C.
• Stability: 1 year
• Shipping: Blue Ice
• Gene Name: ring finger protein 213
• Database Link:
  Q63HN8
• Background: This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants.
• Synonyms: C17orf27; DKFZp762N1115; FLJ13051; KIAA1554; KIAA1618; MGC9929; MGC46622; NET57

Reference Data