ZGPAT Rabbit Polyclonal Antibody
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 200-1000 WB positive control: Human fetal liver tissue, LO2 cell, PC-3 cell, HEPG2 cell lysates IHC: 50-300 Positive control: Human ovarian cancer Predicted cell location: Nucleus |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human ZGPAT |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | 57 kDa |
| Gene Name | zinc finger CCCH-type and G-patch domain containing |
| Database Link | |
| Background | Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. |
| Synonyms | dJ583P15.3; FLJ14972; GPATC6; GPATCH6; KIAA1847; MGC44880; ZC3H9; ZC3HDC9; ZIP |
| Reference Data | |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
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