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DTX2 Rabbit Polyclonal Antibody

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SKU
TA368799
DTX2 rabbit polyclonal antibody
Size:
100 ul
Conjugation:
Unconjugated
  $310.00
4 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 200-400
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human DTX2
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C.
Stability 1 year
Shipping Blue Ice
Gene Name deltex 2, E3 ubiquitin ligase
Database Link
Background DTX2 functions as an E3 ubiquitin ligase (Takeyama et al., 2003 PubMed 12670957). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Synonyms Deltex2; hDTX2; KIAA1528; MGC71098; RNF58
Reference Data
Protein Categories Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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