Cofilin 2 (CFL2) Rabbit Polyclonal Antibody

SKU
TA368021
CFL2 rabbit polyclonal antibody
$310.00
4 Weeks*
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 200-1000
WB positive control: Raji cell,Rat skeletal muscle tissue,Hela cell,Mouse skeletal muscle tissue and Mouse brain tissue lysates
IHC: 20-100
Positive control: Human liver cancer
Predicted cell location: Cytoplasm or Nucleus
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human CFL2
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C.
Stability 1 year
Shipping Blue Ice
Predicted Protein Size 19 kDa
Gene Name cofilin 2
Database Link
Background This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
Synonyms NEM7
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.