Hsp47 (SERPINH1) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 200-1000 WB positive control: Human fetal liver tissue,NIH/3T3,A431,Hela,293T and Hepg2 cell lysates IHC: 25-100 Positive control: Human colorectal cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SERPINH1 |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | 46 kDa |
| Gene Name | serpin family H member 1 |
| Database Link | |
| Background | This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The encoded protein is localized to the endoplasmic reticulum and plays a role in collagen biosynthesis as a collagen-specific molecular chaperone. Autoantibodies to the encoded protein have been found in patients with rheumatoid arthritis. Expression of this gene may be a marker for cancer, and nucleotide polymorphisms in this gene may be associated with preterm birth caused by preterm premature rupture of membranes. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. |
| Synonyms | AsTP3; CBP1; CBP2; colligen; Colligin; colligin-1; colligin-2; gp46; HSP47; PIG14; PPROM; RA-A47; SERPINH2 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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