IL6 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 500-2000 WB positive control: 231, Raji, Jurkat, K562, HUVEC cell lysates IHC: 50-100 Positive control: Human liver cancer Predicted cell location: Secreted |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human IL6 |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C. |
| Stability | 1 year |
| Shipping | Blue Ice |
| Predicted Protein Size | 24 kDa |
| Gene Name | interleukin 6 |
| Database Link | |
| Background | This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). |
| Synonyms | BSF-2; BSF2; CDF; HGF; HSF; IFNB2; IL-6; OTTHUMP00000158544 |
| Reference Data | |
| Protein Categories | Allergies and autoimmune diseases, Chemokines, Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Immune and Inflammatory Responses of the Intestinal Mucosa following Extended Liver Radiofrequency Ablation
Ypsilantis, Lambropoulou, Evagellou et al
Gastroenterol Res Pract (2017) 2017, 3450635 DOI: 10.1155/2017/3450635
Ypsilantis, Lambropoulou, Evagellou et al
Gastroenterol Res Pract (2017) 2017, 3450635 DOI: 10.1155/2017/3450635
Cited by 10
AI Summary: OriGene products, specifically the anti-CD68 (Cat# TA803574), anti-CD4 (Cat# TA500648), and anti-CD8 (Cat# TA500659) antibodies, were used for immunohistochemical detection of immune cell markers in intestinal tissue to assess mucosal immune responses following extended liver radiofrequency ablation.
Showing 1-1 of 1 papers.
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