SPART Rabbit Polyclonal Antibody

SKU
TA362050
SPART Antibody - N-terminal region
  $585.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application WB
Reactivity Human
Antibody Host Rabbit
Clonality Polyclonal
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human SPG20
Specificity Expected reactivity: Human
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration lot specific
Purification Affinity purified
Conjugation Unconjugated
Storage For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 73 kDa
Gene Name spastic paraplegia 20 (Troyer syndrome)
Database Link
Background This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome).
Synonyms KIAA0610; SPARTIN; TAHCCP1
Reference Data
Protein Categories Growth Factors, Intracellular Proteins, Nervous system Diseases
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