HOOK3 Rabbit Polyclonal Antibody

SKU TA355011

Rabbit Polyclonal Anti-HOOK3 Antibody

Product Data

• Application: IF, IHC, WB
• Recommended Dilution: WB: 1-2µg/mL.IHC: 10µg/ml.
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: HOOK3 antibody was raised against a 19 amino acid peptide from near the amino terminus of human HOOK3. The immunogen is located within amino acids 210 - 260 of HOOK3.
• Buffer: HOOK3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: HOOK3 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: Predicted: 79 kDa; Observed: 77 kDa
• Gene Name: hook microtubule-tethering protein 3
• Database Link:
  NP_115786
  Q86VS8
• Background: The HOOK proteins (HOOK1, HOOK2 and HOOK3) comprise a family of cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules mediating the spatial organization of diverse membrane-trafficking systems; their more divergent C-terminal domains mediate binding to organelles (1,2). HOOK3 exists as a homodimer and participates in defining the architecture and localization of the Golgi complex through its central coiled-coil domain (3). HOOK3 may regulate clearance of endocytosed receptors such as MSR1 (3,4).
• Synonyms: FLJ31058; hHK3; HK3
• Note: HOOK3 antibody can be used for the detection of HOOK3 by Western blot at 1 - 2 µg/mL. Antibody can also be used for immunohistochemistry at 10 µg/ml.

Reference Data