FGFR3 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | WB 0.1-1 µg/ml ELISA N/A IP 2-5 µg/ml IHC 1-5 µg/ml FC Not tested |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | A 14aa synthetic peptide derived from aa 359-372 of human FGFR-3 protein. |
| Buffer | This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. |
| Purification | The Rabbit IgG is purified by Epitope Affinity Purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 120 kDa |
| Gene Name | fibroblast growth factor receptor 3 |
| Database Link | |
| Background | The fibroblast growth factors (FGFs) are members of a large family of structurally related polypeptides that are potent physiological regulators of growth and differentiation for a wide variet of cells of mesodermal, ectodermal and endodermal origin. Four genes encoding for high affinity cell surface FGF receptors (FGFRs) have been identified: FGFR-1, FGFR-2, FGFR-3 and FGFR-4.FGFRs are emembers of the tyrosine kinase family of growth factor receptors. FGFR-3 is widely expressed in many fetal and adult human and animal tissues. |
| Synonyms | ACH; CD333; CEK2; HSFGFR3EX; JTK4 |
| Reference Data | |
| Protein Categories | Cancer: Bladder, Cancer: Haematopoietic and Lymphoid, CD Markers, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins, Secreated Proteins |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Bladder cancer, Endocytosis, MAPK signaling pathway, Pathways in cancer, Regulation of actin cytoskeleton |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Proteasome inhibition restored the reduced expression of fibroblast growth factor receptor 3 in rheumatoid arthritis synovial fibroblasts
Neidhart, Karouzakis, Fucentese et al
Research Square (2020)
Neidhart, Karouzakis, Fucentese et al
Research Square (2020)
Snippet: albumin. The sections were incubated either with rabbit IgG1 (negative control) or polyclonal rabbit antibodies to human CD333 /FGFR3 (Acris Antibodies), end-concentration 10 µg/ml in PBS, for 1 hour at 22 °C. The slides were
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