FUT4 Mouse Monoclonal Antibody
Specifications
| Product Data | |
| Recommended Dilution | WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml |
|---|---|
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgM |
| Clonality | Monoclonal |
| Immunogen | The human myelomonocytic leukemia cells. |
| Buffer | This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. |
| Purification | The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 59 kDa |
| Gene Name | fucosyltransferase 4 |
| Database Link | |
| Background | CD15 is an antigen present on myelomonocytic cells and Lacto-Nfucopentose III (also known as hapten X). It is present on greater than 90% of granulocytes including neutrophils and eosinophils, and to a lesser degree, on monocytes. CD15 is expressed in Reed-Sternberg cells of Hodgkin’s disease (of the nodular sclerosis, mixed cellularity and lymphocyte-depleted subtypes). This antibody recognizes myeloid cells, mainly granulocytes but not on B cells, T cells, monocytes, erythrocytes or platelets. Positive staining for CD15 combined with a negative reaction for lymphocytic markers may provide support for Hodgkin’s disease. Fifty percent or more of adenocarcinomas have been described as showing significant cytoplasmic positivity for CD15. It does not detect most mesotheliomas. |
| Synonyms | CD15; ELFT; FCT3A; FUC-TIV; FUTIV; LeX; SSEA-1 |
| Reference Data | |
| Protein Categories | ADC Targets, Membrane Proteins |
| Protein Families | Transmembrane |
| Protein Pathways | Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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