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Caspase 10 (CASP10) Rabbit Polyclonal Antibody

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SKU
TA354379
Rabbit anti Caspase 10 Polyclonal Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $450.00
5 Days*
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Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen A synthetic peptide corresponding to C-term of human Caspase 10. This sequence is identical to mouse and rat.
Buffer This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 59 kDa for precursor; 23,17 kDa
Gene Name caspase 10
Database Link
Background A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6 and caspase-7, caspase-9, and caspase-10. Ced-3 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli.
Synonyms ALPS2; FLICE2; MCH4
Reference Data
Protein Categories Cancer: Haematopoietic and Lymphoid, Enzyme: Peptidases, Immune system diseases, Intracellular Proteins
Protein Families Druggable Genome, Protease
Protein Pathways Apoptosis, RIG-I-like receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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