KCNMB4 Rabbit Polyclonal Antibody

SKU
TA351322
Rabbit Polyclonal Anti-KCNMB4 Antibody
  $205.00
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Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: Mouse brain tissue
IHC: 50-200
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human KCNMB4
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 24 kDa
Gene Name potassium calcium-activated channel subfamily M regulatory beta subunit 4
Database Link
Background MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit.
Synonyms beta member 4; calcium-activated potassium channel beta 4 subunit; large conductance calcium-dependent potassium ion channel beta 4 subunit; potassium large conductance calcium-activated channel; subfamily M
Reference Data
Protein Categories Membrane Proteins
Protein Families Druggable Genome, Ion Channels: Other, Transmembrane
Protein Pathways Vascular smooth muscle contraction
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