MUM1 (IRF4) Rabbit Polyclonal Antibody

SKU TA351302

Rabbit Polyclonal Anti-IRF4 Antibody

Product Data

• Application: WB
• Recommended Dilution: WB: 200-1000; WB positive control: Mouse lung tissue
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human IRF4
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 52 kDa
• Gene Name: interferon regulatory factor 4
• Database Link:
  NP_002451
  Q15306
• Background: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: LSIRF; MUM1; NF-EM5; SHEP8

Reference Data

• Protein Families: Druggable Genome, Transcription Factors