Peroxiredoxin 2 (PRDX2) Rabbit Polyclonal Antibody

SKU
TA350723
Rabbit Polyclonal Anti-PRDX2 Antibody
  $205.00
In Stock*
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Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: 293T, hela, PC3 and NIH/3T3 cells
IHC: 100-300
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human PRDX2
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 22 kDa
Gene Name peroxiredoxin 2
Database Link
Background This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.
Synonyms NKEFB; PRP; PRX2; PRXII; PTX1; TDPX1; TPX1; TSA
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
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