NDUFAF1 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB: 500-2000 WB positive control: 231 and Jurkat cells |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human NDUFAF1 |
| Buffer | pH7.4 PBS, 0.05% NaN3, 40% Glyceroln |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 38 kDa |
| Gene Name | NADH:ubiquinone oxidoreductase complex assembly factor 1 |
| Database Link | |
| Background | This gene encodes a complex I assembly factor protein. Complex I (NADH-ubiquinone oxidoreductase) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. The encoded protein is required for assembly of complex I, and mutations in this gene are a cause of mitochondrial complex I deficiency. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. |
| Synonyms | CGI-65; CGI65; CIA30 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
ECSIT prevents Alzheimer's disease pathology by regulating neuronal mitochondrial ROS and mitophagy
Lepelley, Vaughn, Staniszewski et al
bioRxiv (2020)
Lepelley, Vaughn, Staniszewski et al
bioRxiv (2020)
Cited by 3
Snippet: Primary antibodies were: anti-VDAC1 (dilution 1:2,000, Abcam, clone 20B12AF2), NDUFS3 (1:1,000, Abcam, clone 3F9DD2), SDHA (1:2,000, Abcam, clone EPR9043), UQCRC2 (1:2,000, Abcam, clone 13G12AF12BB11), MTCOI (1:4,000, Abcam, clone 1D6E1A8), NDUFAF1 (1:2,000, Origene), TOM20 (1:500, Sigma-Aldrich, clone 4F3), HSP60 (1:500, Santa Cruz Biotechnology, clone H-1), GAPDH (1:5,000, Fitzgerald), beta-Tubulin (1:1,000, Sigma-Aldrich, clone TUB2.1), Actin (1:1,000, Santa Cruz Biotechnology, clone C-4), GFP (1:1,000, Santa Cruz Biotechnology, clone B-2),
Showing 1-1 of 1 papers.
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