Coronin 3 (CORO1C) Rabbit Polyclonal Antibody

SKU
TA349821
Rabbit Polyclonal Anti-CORO1C Antibody
  $205.00
In Stock*
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Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: Lovo cells
IHC: 100-300
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human CORO1C
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 53 kDa
Gene Name coronin 1C
Database Link
Background This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene.
Synonyms HCRNN4
Reference Data
Protein Categories Intracellular Proteins
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Documents
Resources

file-alt Citations

Noninvasive urinary protein signatures associated with colorectal cancer diagnosis and metastasis
Sun, Guo, Liu et al
Nat Commun (2022) 13 (1), 2757 DOI: 10.1038/s41467-022-30391-8
Cited by 80
AI Summary: OriGene contributed to this study by providing the anti-CORO1C antibody (Cat No. TA349821), which was used for tissue microarray staining to validate urinary protein biomarkers associated with colorectal cancer diagnosis and metastasis.
Snippet: …However, high heterogeneity of primary tumor;TMAs were incubated overnight with anti-CORO1C (Cat No. TA349821;OriGene Technologies, Inc, Rockville, MD, USA), anti-RAD23B (Cat No. …sc-166760) antibodies at 4 °C. …
FigureFigureFigure
IHC
Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis
Li, Tian, Jing et al
Cancer Lett (2021) 516, 13-27 DOI: 10.1016/j.canlet.2021.05.033
Cited by 31
AI Summary: In this study, OriGene’s RAD23B shRNA lentiviral particles (TL313328V) and CORO1C shRNA lentiviral particles (TL320280V) were used to knock down gene expression, enabling the authors to investigate the roles of RAD23B and CORO1C in colorectal cancer cell invasion and metastasis.
Showing 1-2 of 2 papers.
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