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PLEKHO1 Rabbit Polyclonal Antibody

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SKU
TA349809
Rabbit Polyclonal Anti-PLEKHO1 Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $205.00
In Stock*
Bulk/Customize

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20 ug
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View other "PLEKHO1 or NM_016274" antibodies

Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 200-1000
WB positive control: Hela cells, mouse muscle and kidney tissue
IHC: 100-300
Positive control: Human thyroid cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein of human PLEKHO1
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 46 kDa
Gene Name pleckstrin homology domain containing O1
Database Link
Background Pleckstrin homology domain-containing family O member 1 is a protein that in humans is encoded by thePLEKHO1 gene. Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival.
Synonyms CKIP-1; CKIP1; JBP; OC120
Reference Data
Protein Categories Intracellular Proteins
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Documents
Resources

file-alt Citations

microRNA-494 Favors HO-1 Expression in Neuroblastoma Cells Exposed to Oxidative Stress in a Bach1-Independent Way
Piras, Furfaro, Caggiano et al
Front Oncol (2018) 8, 199 DOI: 10.3389/fonc.2018.00199
AI Summary: In this study, OriGene's rabbit anti-HO-1 antibody was used to detect HO-1 protein levels by immunodetection, enabling the authors to assess how miR-494 influences HO-1 expression in neuroblastoma cells under oxidative stress.
Snippet: mmunodetection was performed using mouse anti-hnRNPQ (1:1,000, Santa Cruz), rabbit anti-PTEN (1:1,000, Cell Signaling Technology, MA, USA), rabbit anti-Bach1 (1:4,000, Bethyl Lab, Montgomery, TX, USA), and rabbit anti-HO-1 (1:2,000, Origene, Herford, Germany) and specific secondary antibodies (GE Healthcare). The membranes were re-probed with the loading control antibodies, rabbit anti-GAPDH (1:1,...
FigureFigure
WB
Showing 1-1 of 1 papers.
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