AKAP4 Rabbit Polyclonal Antibody

CAT#: TA349098

Rabbit Polyclonal Anti-AKAP4 Antibody

Product Images

Western blot analysis of AKAP4 in human testis tissue lysate with AKAP4 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunohistochemistry of AKAP4 in human testis tissue with AKAP4 antibody at 5 ug/mL.

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  Immunofluorescence of AKAP4 in human testis tissue with AKAP4 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: AKAP4 antibody was raised against a 17 amino acid peptide near the amino terminus of human AKAP4.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: AKAP4 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 94 kDa; Observed: 100 kDa
• Gene Name: A-kinase anchoring protein 4
• Database Link:
  NP_003877
  Entrez Gene 8852 Human
  UniProt ID Q5JQC9
• Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell (1). AKAP4, also known as hAKAP82, is a major sperm fibrous sheath protein that localizes to the entire length of the flagellum of human sperm (2). It has been suggested that AKAP4 plays multiple roles in sperm motility and regulation of signal transduction pathways (2). AKAP4 has also been postulated to be a potential biomarker for breast cancer (3).
• Synonyms: AC133; CD133; CORD12; MCDR2; MSTP061; PROML1; RP41; STGD4