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ASCIZ (ATMIN) Rabbit Polyclonal Antibody

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SKU
TA349047
Rabbit Polyclonal Anti-ATMIN Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $640.00
5 Days*
Bulk/Customize

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Specifications
Specifications
Product Data
Application IF, WB
Recommended Dilution WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 2.5 ug/mL
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen ATMIN antibody was raised against a 19 amino acid peptide near the amino terminus of human ATMIN.
Buffer PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification ATMIN antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size Predicted: 73, 79, 91 kDa; Observed: 72 kDa
Gene Name ATM interactor
Database Link
Background The ATM/ATR-substrate CHK2-interacting zinc finger protein (ATMIN), also known as ASCIZ, forms DNA damage-induced nuclear foci that contain the DNA repair protein Rad51 (1). ATMIN is also thought to be involved in embryonic development, as an absence of ATMIN causes late-embryonic lethality in mice with a range of organ development defects (2). It also activates the transcription DYNLL1, a light chain of the dynein motor complex and sequence-specific regulator of protein dimerization of numerous targets. DYNLL1 can bind to and inhibit the transcription activation domain of ATMIN, forming a simple dynamic feedback loop for DYNLL1 expression (3).
Synonyms HBEBP3; HBEBP36; KIBRA; MEMRYQTL; PPP1R168
Reference Data
Protein Categories Intracellular Proteins
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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