C5orf20 (DCANP1) Rabbit Polyclonal Antibody

SKU TA349044

Rabbit Polyclonal Anti-DCNP1 Antibody

Product Data

• Application: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: DCNP1 antibody was raised against an 18 amino acid peptide near the amino terminus of human DCNP1.
• Buffer: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: DCNP1 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: Predicted: 27 kDa; Observed: 24 kDa
• Gene Name: dendritic cell-associated nuclear protein
• Database Link:
  NP_570900
  Q8TF63
• Background: The DCNP1 (dendritic cell nuclear protein 1) gene is specifically expressed in dendritic cells, potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response (1). It is localized mainly in the perinucleus. One of the alleles (A/T) of this gene causes premature translation termination at aa 117 and has been associated with an increased prevalence of major depression in humans (2,3). DCNP1 may play a role in the pathogenesis of depressive disorders by enhancing corticotropin-releasing hormone expression in the hypothalamic paraventricular nucleus (4).
• Synonyms: bA350J20.7; LETAL; N2DL-4; NKG2DL4; RAET1E2; RL-4; ULBP4

Reference Data