robld3 (LAMTOR2) Rabbit Polyclonal Antibody

SKU TA349022

Rabbit Polyclonal Anti-LAMTOR2 Antibody

Product Data

• Application: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: LAMTOR2 antibody was raised against an 18 amino acid peptide near the center of human LAMTOR2.
• Buffer: PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: LAMTOR2 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: Predicted: 14 kDa; Observed: 16 kDa
• Gene Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
• Database Link:
  NP_054736
  Q9Y2Q5
• Background: The late endosomal/lysosomal adaptor MAPK and MTOR activator 2 (LAMTOR2) protein belongs to the LAMTOR family of proteins, and together with LAMTOR3 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling (1,2). This complex is involved in the regulation of late endosomal traffic and cellular proliferation (3) and plays a role in cellular host defense against Salmonella infection (4).
• Synonyms: ANG-5; ANGPT5; ANL3; FHBL2

Reference Data