Phospho EPHA2/3 (Tyr588/596) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB: 1:500-1:2000 |
| Reactivity | Human, Mouse, Rat |
| Modification | Phospho-specific |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The immunogen for anti-Phospho-EPHA2/3(Tyr588/596) Antibody: A synthesized peptide derived from human EPHA2/3 around the phosphorylation site of Tyrosine 588 and 596 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20?. Stable for 12 months from date of receipt |
| Concentration | lot specific |
| Purification | Immunogen affinity purified |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 130 kDa |
| Gene Name | EPH receptor A2 |
| Database Link | |
| Background | EphA2 a receptor tyrosine kinase. Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A3, -A4 AND -A5. The Eph receptor tyrosine kinase family, the largest in the tyrosine kinase group, has fourteen members. They bind membrane-anchored ligands, ephrins, at sites of cell-cell contact, regulating the repulsion and adhesion of cells that underlie the establishment, maintenance, and remodeling of patterns of cellular organization. Eph signals are particularly important in regulating cell adhesion and cell migration during development, axon guidance, homeostasis and disease. |
| Synonyms | ARCC2; CTPA; CTPP1; CTRCT6; ECK |
| Note | Phospho-EPHA2/3(Tyr588/596) Antibody detects endogenous levels of EPHA2 and 3 only when phosphorylated at Tyrosine 588 and 596 |
| Reference Data | |
| Protein Categories | ADC Targets, Chemokines, Cytokines, Enzyme: Kinases, Growth Factors, Membrane Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Axon guidance |
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