H2BC5 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | Dot, ELISA, WB |
|---|---|
| Recommended Dilution | ChIP/ChIP-seq (2ug/ChIP); ELISA (1:1,000); Dot blotting (1:20,000); Western blotting (1:500) |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The immunogen for anti-H2BK15ac antibody: the region of histone H2B containing the acetylated lysine 15 (H2BK15ac), using a KLH-conjugated synthetic peptide. |
| Concentration | lot specific |
| Purification | Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | histone cluster 1, H2bd |
| Database Link | |
| Background | Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histone tails undergo numerous post-translational modifications, which either directly or indirectly alter chromatin structure to facilitate transcriptional activation or repression or other nuclear processes. In addition to the genetic code, combinations of the different histone modifications reveal the so-called "histone code". Histone methylation and demethylation is dynamically regulated by respectively histone methyl transferases and histone demethylases. Acetylation of histone H2B is associated with active genes. |
| Synonyms | b; dJ221C16.6; H2B; H2B.1B; H2BFB; HIRIP2 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Pathways | Systemic lupus erythematosus |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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