FKBP25 (FKBP3) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, WB |
|---|---|
| Recommended Dilution | ELISA (1:100 ?? 1:200) ; Western blotting (1:500) |
| Reactivity | Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The immunogen for anti-FKBP3 antibody: mouse FKBP3 (FK506 Binding Protein 3), using a KLH-conjugated synthetic peptide containing an amino acid sequence from the central part of the protein |
| Concentration | lot specific |
| Purification | Whole antiserum from rabbit containing 0.05% azide. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | FK506 binding protein 3 |
| Database Link | |
| Background | FKBP3 (UniProtKB/Swiss-Prot entry Q00688) is a member of the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It acts as a receptor for FK506 and rapamycin, two immunosuppressants which inhibit T-cell proliferation. FKBP3 localizes to the nucleus and interacts with the transcription factor YY1 and with histone deacetylases. Therefore, it may play a role in chromatin modification and be important for the regulation of transcription. |
| Synonyms | FKBP-3; FKBP-25; FKBP25; PPIase |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
Reviews
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