BAF53b (ACTL6B) Rabbit Polyclonal Antibody
Rabbit Polyclonal ACTL6B Antibody
Product Datasheet for 'TA347076'
|Recommend Dilution||ELISA (1:500 ?? 1:1,000) ; Western blotting (1:1,000)|
|Immunogen||The immunogen for anti-ACTL6B antibody: human ACTL6B (actin-like 6B), using a KLH-conjugated synthetic peptide containing a sequence from the central part of the protein.|
|Purification||Whole antiserum from rabbit containing 0.05% azide.|
|Gene Name||actin like 6B|
|Background||ACTL6B (UniProt/Swiss-Prot entry O94805) belongs to the family of actin-related proteins (ARPs) which are involved in diverse cellular processes such as vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL6B is a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is thought to antagonize chromatin-mediated transcriptional repression thereby facilitating transcriptional activation of specific genes. Further, ACTL6B may be involved in gene regulation by structural modulation of their chromatin, specifically in the brain.|
|Synonyms||ACTL6; BAF53B; arpNalpha|
|Protein Families||Druggable Genome|
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