BAF53b (ACTL6B) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, WB |
|---|---|
| Recommended Dilution | ELISA (1:500 ?? 1:1,000) ; Western blotting (1:1,000) |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The immunogen for anti-ACTL6B antibody: human ACTL6B (actin-like 6B), using a KLH-conjugated synthetic peptide containing a sequence from the central part of the protein. |
| Concentration | lot specific |
| Purification | Whole antiserum from rabbit containing 0.05% azide. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | actin like 6B |
| Database Link | |
| Background | ACTL6B (UniProt/Swiss-Prot entry O94805) belongs to the family of actin-related proteins (ARPs) which are involved in diverse cellular processes such as vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL6B is a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is thought to antagonize chromatin-mediated transcriptional repression thereby facilitating transcriptional activation of specific genes. Further, ACTL6B may be involved in gene regulation by structural modulation of their chromatin, specifically in the brain. |
| Synonyms | ACTL6; BAF53B |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Nervous system Diseases |
| Protein Families | Druggable Genome |
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