FAM120A Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The immunogen for anti-FAM120A antibody: synthetic peptide directed towards the middle region of human FAM120A. Synthetic peptide located within the following region: SGGATNHISGNKIGWEKTGSHSEPQARGDPGDQTKAEGSSTASSGSQLAE |
| Buffer | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Purification | Affinity Purified |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 122 kDa |
| Gene Name | family with sequence similarity 120A |
| Database Link | |
| Background | FAM120A may participate in mRNA transport in the cytoplasm. FAM120A is the critical component of the oxidative stress-induced survival signaling. It activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. FAM120A binds RNA and promotes the secretion of IGF-II. It may play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses. |
| Synonyms | C9orf10; OSSA |
| Note | Immunogen Sequence Homology: Dog: 100%; Pig: 100%; Horse: 100%; Human: 100%; Bovine: 100%; Rabbit: 92%; Rat: 85%; Mouse: 85% |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
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