Hsc70 (HSPA8) Rabbit Polyclonal Antibody

SKU
TA332519
Rabbit polyclonal anti-HSPA8(HSC70) antibody, Loading control
  $410.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application ELISA, ICC/IF, IHC, WB
Recommended Dilution WB,1:500 - 1:1000
IHC-P,1:50 - 1:200
IF/ICC,1:50 - 1:200
ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity Human, Monkey, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Buffer Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Store at -20℃. Avoid freeze / thaw cycles.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 71kDa
Gene Name heat shock protein family A (Hsp70) member 8
Database Link
Background This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms HEL-33; HEL-S-72p; HSC54; HSC70; HSC71; HSP71; HSP73; HSPA10; LAP-1; LAP1; NIP71
Reference Data
Protein Categories Intracellular Proteins
Protein Families Stem cell - Pluripotency
Protein Pathways Antigen processing and presentation, Endocytosis, MAPK signaling pathway, Spliceosome
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Documents
Resources

file-alt Citations

Sex Differences in Sphingosine-1-Phosphate Levels Are Dependent on Ceramide Synthase 1 and Ceramidase in Lung Physiology and Tumor Conditions
Terlizzi, Colarusso, Ferraro et al
Int J Mol Sci (2023) 24 (13) DOI: 10.3390/ijms241310841
Cited by 4
AI Summary: OriGene products GAPDH (#TA890003) and HSC-70 (#TA332519) antibodies were used as loading controls in protein expression analyses to ensure accurate quantification of target proteins in the study.
Snippet: sor form: 55 kDa;N-acylsphingosine amidohydrolase 1, ASAH1;Elabscience;Houston, TX, USA;#E-AB-10959) was evaluated in ADK and SCC tissues. Glyceraldehyde-3-phosphate dehydrogenase (37 kDa;GAPDH;OriGene Technologies, Rockville, MD, USA;#TA890003) or heat shock cognate protein 70 (70 kDa;HSC-70;#TA332519) were used as the loading control. Data were
FigureFigureFigure
WB
Induction of Inflammation Disrupts the Negative Interplay between STING and S1P Axis That Is Observed during Physiological Conditions in the Lung
Terlizzi, Colarusso, Falanga et al
Int J Mol Sci (2023) 24 (9) DOI: 10.3390/ijms24098303
Cited by 6
AI Summary: OriGene's Heat shock cognate protein 70 (HSC70; #TA332519) was used as a loading control in Western blot experiments to ensure accurate assessment of ceramidase expression in lung tissue samples.
Snippet: ated lung epithelial cells;also, ceramidase expression was evaluated in lung homogenates of NMU- and NMU+H151-exposed mice (refers to mouse model below). Heat shock cognate protein 70 (HSC70;70kDa;OriGene Technologies, Rockville, MD, USA;#TA332519) was used as loading control. Data were analyzed by means of ImageJ software 1.53a http://imagej.nih.gov/ij (accessed on 1 October 2022) (NIH, Bethe
FigureFigureFigure
WB
Showing 1-2 of 2 papers.
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