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Cacna1c Rabbit Polyclonal Antibody

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SKU
TA328723
Rabbit Polyclonal Anti-CaV1.2
Size:
50 ul
Conjugation:
Unconjugated
  $1,145.00
3 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 1:200-1:2000; IHC: 1:100-1:3,000; FC: 1:50-1:600
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Peptide (C)TTKINMDDLQPSENEDKS, corresponding to amino acid residues 848-865 of rat Cav1.2. Intracellular loop between domains II and III.
Buffer Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Reconstitution Method Add 50 ul double distilled water (DDW) to the lyophilized powder.
Purification Affinity purified on immobilized peptide.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Gene Name calcium voltage-gated channel subunit alpha1 C
Database Link
Background All L-type calcium channels are encoded by one of the CaV1 channel genes. These channels play a major role as a Ca2+ entry pathway in skeletal cardiac and smooth muscles as well as in neurons, endocrine cells and possibly in non-excitable cells such as hematopoetic and epithelial cells. All CaV1 channels are influenced by dIHCydropyridines (DHP) and are also referred to as DHP receptor. While the CaV1.1 and CaV1.4 isoforms are expressed in restricted tissues (skeletal muscle and retina, respectively), the expression of CaV1.2 is ubiquitous and CaV1.3 channels are found in heart, brain and pancreas. Several peptidyl toxins are described that are specific L-type channels blockers, but so far no selective blocker for one of the CaV1 isoforms have been described. These include the Mamba toxins Calcicludine, Calciseptine and FS-2 .
Synonyms CACH2; CACN2; CACNL1A1; CaV1.2; CCHL1A1; MGC120730; OTTHUMP00000196730; OTTHUMP00000196731; OTTHUMP00000196732; OTTHUMP00000196733; OTTHUMP00000196734; OTTHUMP00000196735; OTTHUMP00000196736; OTTHUMP00000196737; OTTHUMP00000196739; OTTHUMP00000196744; OTTHUMP00000196746; OTTHUMP00000196747; OTTHUMP00000196748; OTTHUMP00000196749; OTTHUMP00000196751; TS
Reference Data
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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