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P2Y11 (P2RY11) Rabbit Polyclonal Antibody

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SKU
TA328678
Rabbit Polyclonal Anti-P2Y11 Receptor
Size:
50 ul
Conjugation:
Unconjugated
  $1,145.00
3 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution WB: 1:200-1:2000; IHC: 1:100-1:3,000; FC: 1:50-1:600
Reactivity Human, Rat
Antibody Host Rabbit
Clonality Polyclonal
Immunogen Peptide (C)NATAAPKPSEPQSRELS, corresponding to amino acid residues 357-373 of human P2Y11. Intracellular, C-terminus.
Buffer Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Reconstitution Method Add 50 ul double distilled water (DDW) to the lyophilized powder.
Purification Affinity purified on immobilized antigen.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Ambient
Gene Name purinergic receptor P2Y11
Database Link
Background The P2Y receptors belong to the G-protein coupled receptors superfamily.They mediate the actions of the extracellular nucleotides (ATP, ADP, UTP and UDP). Eight functional mammalian P2Y receptors have been described: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13, and the UDP-glucose receptor, now renamed P2Y14.The human P2Y11 receptor is unique among the P2Y receptors since it is dually coupled to phospholipase C and adenylyl cyclase. P2Y11 receptor is highly pressed in spleen and for much lower extent at platelets.Expression of P2Y11 receptor was also shown in endothelial cells. In granulocytes HL-60), P2Y11 receptor is thought to have a role in granulocytic differentiation.
Synonyms P2Y11
Reference Data
Protein Categories GPCR, Membrane Proteins
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Neuroactive ligand-receptor interaction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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