LGICZ1 (ZACN) Rabbit Polyclonal Antibody
$1,145.00
3 Weeks*
Specifications
| Product Data | |
| Application | FC, IF, WB |
|---|---|
| Recommended Dilution | WB: 1:200-1:2000; FC: 1:50-1:600 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Peptide CNFELLHFPRDHSN, corresponding to amino acid residues 157-170 of human zinc-activated channel (ZAC).Extracellular, N-terminus. |
| Buffer | Lyophilized. Concentration before lyophilization ~0.8mg/ml (lot dependent, please refer to CoA along with shipment for actual concentration). Buffer before lyophilization: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3. |
| Reconstitution Method | Add 50 ul double distilled water (DDW) to the lyophilized powder. |
| Purification | Affinity purified on immobilized antigen. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Ambient |
| Gene Name | zinc activated ion channel |
| Database Link | |
| Background | Over forty homologous proteins belong to the superfamily of ligand-gated ion channels. These members are broken down into different subfamilies, for example: acetylcholine, serotonin and glycine receptors. A new member has been added to this superfamily – ZAC (zinc-activated channel) which is expressed in human and dog but not in rodents. Like all other ligand-gated ion channels, ZAC has four transmembrane domains and extracellular N- and C-termini. As its name states, the channel is activated by high concentrations of zinc. ZAC mRNA was found to be expressed in placenta, spinal cord, stomach, and fetal brain. In another study, ZAC was identified using a computer-assisted program and was detected in similar areas (including pancreas and kidney), but also displayed minor discrepancies. Being that the channel is expressed in human and dog, deciphering its cellular/physiological functions will be challenging. |
| Synonyms | L2; LGICZ; LGICZ1; ZAC; ZAC1 |
| Note | This antibody was tested in live cell imaging. Please see IF/ICC data for detail. |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Druggable Genome, Ion Channels: Other, Transmembrane |
Reviews
Documents
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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