Phospho DNA-PKcs (Thr2609) Mouse Monoclonal Antibody [Clone ID: 10B1]
$575.00
5 Days*
Specifications
| Product Data | |
| Clone Name | 10B1 |
|---|---|
| Application | WB |
| Recommended Dilution | WB, IF |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Immunogen | Modified peptide |
| Buffer | This DNA-PKcs antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. Final antibody concentration is 0.5 mg/ml. |
| Concentration | lot specific |
| Purification | The antibody was purified by affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 470 kD |
| Gene Name | protein kinase, DNA activated, catalytic polypeptide |
| Database Link | |
| Background | DNA-protein kinase catalytic subunit (DNA-PKcs) also known as DNA-activated kinase is a nuclear 460-470 kD serine threonine kinase involved in double-stranded DNA break repair, VDJ recombination, and transcriptional modulation. DNA-PKcs must bind DNA ends to become active. DNA-PKcs is modified by phosphorylation and has been shown to interact with Ku70/Ku80, KIP, DNA-ligase IV, and XRCC4 proteins. Phosphorylated DNA-PKcs is upregulated after DNA damaage. The 10B1 monoclonal antibody recognizes phosphorylated human DNA-PKcs (Thr2609) and has been shown to be useful for immunofluorescence staining and Western blotting. |
| Synonyms | DNA-PKcs; DNAPK; DNPK1; HYRC; HYRC1; p350; p460; XRCC7 |
| Note | reacts with Thr2609-phosphorylated DNA-PKcs |
| Reference Data | |
| Protein Categories | Enzyme: Kinases, Immune system diseases, Intracellular Proteins |
Reviews
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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